Paricalcitol is used in patients with longterm kidney disease to treat or prevent high levels of a certain natural substance made by the body parathyroid hormone. As of 20, this field contains the consumer friendly descriptions for the ama cpt codes. Aug 02, 2017 zemplar capsules patient information including how should i take what should i discuss with my healthcare provider before using paricalcitol zemplar. It helps to reduce parathyroid hormone levels and may help your body absorb calcium and phosphorus. The l3harris an plm 4 radar signal simulator rss is an advanced portable, costeffective radar simulator that tests radar warning receivers, electronic surveillance measures and electronic countermeasures systems.
Zemplar paricalcitol injection, for intravenous use initial u. Abbott has launched a new oral form of zemplar onto the uk market, offering a more convenient therapy option to patients with secondary hyperparathyroidism, a common complication of chronic kidney disease. Oct 01, 2019 zemplar paricalcitol injection is a sterile, clear, colorless, aqueous solution for intravenous use. Apr 19, 2018 zemplar 5 microgramml solution for injection. Aug 29, 2019 zemplar paricalcitol injection fliptop vial. You should not use paricalcitol if you are allergic to it, or if you have high levels of vitamin d or calcium in your body. The six youngest zemplar treated patients in the study were 5 12 years old. Approximately 600 patients were treated with zemplar in phase iiiii iv clinical trials. Consumer information about the medication paricalcitol injection zemplar, includes side effects, drug interactions, recommended dosages, and storage information. Pharmacokinetics distribution the pharmacokinetics of paricalcitol have been studied in patients with chronic renal failure crf requiring hemodialysis. Study of zemplar iv in patients with end stage chronic kidney. Hyperparathyroidism is a condition that is caused when the parathyroid glands located in the neck make too much parathyroid hormone pth. The difference between plm software and pdm software. Vitamin d is important for the absorption of calcium from the stomach and for the functioning of calcium in the body paricalcitol is used to help maintain healthy levels of parathyroid hormone in people with chronic kidney disease who are on dialysis paricalcitol oral is for use in adults and children at least 10 years old.
Because zemplar paricalcitol can affect your blood calcium and phosphorus levels, you may need more blood tests and doctor followup visits than alternative medicines. Paricalcitol may also be used for purposes not listed in this medication guide. Therefore, it is imperative that you do educated comparisons to choose the best product lifecycle management software for your organizations needs. Product lifecycle management plm software manages information throughout the entire lifecycle from ideation, design and manufacture through service and. We ensure the listing of all the products of zemplar passing the nations boundaries according to international products standards. Zemplar injection paricalcitol dose, indications, adverse. Both the brand and generic forms of zemplar paricalcitol can be more expensive compared to similar medicines. The formulation calculates automatically allergens, ingredients, nutrient facts, costs, labeling. Zemplar capsules are an active form of vitamin d used to prevent and treat secondary hyperparathyroidism increased parathyroid hormone levels in adults and children 10 years of age and older with stage 3 or stage 4 chronic kidney disease and in stage 5 patients on dialysis. Product lifecycle management wikipedia, the free encyclopedia. Abbott launches new form of zemplar in uk pharmatimes.
Individualize and titrate iv dose based on ipth, serum calcium, and phosphorus levels to maintain an ipth level within target range. Paricalcitol, usp, the active ingredient in zemplar injection, is a synthetically manufactured analog of calcitriol, the metabolically active form of vitamin d indicated for the prevention and treatment of secondary hyperparathyroidism associated with chronic kidney diseaseckd stage 5. For more information, talk with your health care provider. Zemplar 5 microgramml solution for injection summary of product. Paricalcitol is a synthetic manmade form of vitamin d. Paricalcitol, usp, the active ingredient in zemplar capsules, is a synthetically manufactured, metabolically active vitamin d analog of calcitriol with modifications to the side chain d 2 and the a 19nor ring. On its own plm is simply software that aims to integrate people, data, processes and business systems. The six youngest zemplar iv treated patients in the study were 5 12 years old. Iv paricalcitol used for prevention and treatment of secondary hyperparathyroidism associated with stage 5 chronic kidney disease ckd.
The initial dose of paricalcitol is based on the following formula. Overall, 6% of the zemplar treated patients reported adverse reactions. Role of plm plm solutions like siemens plm softwares teamcenter software play a crucial role in ensuring that hightech and electronics companies are able to define. Discover how teamcenter software is a modern, adaptable product lifecycle management plm system connecting people and processes, across functional. Zemplar injection clinical pharmacology mechanism of action.
Each ml of solution for injection contains 5 micrograms of paricalcitol. Paricalcitol is a synthetic, biologically active vitamin d 2 analog. It compiles its database according to authentic shipment data from indian customs. The related drug information index provides comprehensive access to all drug information related to a specific drug types of content include full prescribing information, drug summaries, full prescribing information continuing medication education full pi cme, medication guides, risk evaluation and mitigation strategies rems summaries, rems continuing medication education rems cme, and. Plm software integrates people, data processes and business systems. What is the most important information i should know about paricalcitol zemplar. An plm 4 radar signal simulator rss the l3harris an plm 4 radar signal simulator rss is an advanced portable, costeffective radar simulator that tests radar warning receivers, electronic surveillance measures and electronic countermeasures systems.
Ckd stage 34 and ckd stage 5 renal replacement therapy. This is achieved by creating a centralized system to organize all data on all products, from initial conceptualization, to manufacturing, to sale and eventually to. Iv bolus dose no more frequently then every other day at any time. Zemplar capsules paricalcitol side effects, images, uses. The new holland intelliview iv display is an intuitive, color touchscreen display that can be factoryintegrated in numerous models of new holland equipment. Adjust maintenance dose based on ipth and serum calcium concentrations. It is actually the process of managing the whole lifecycle of a production from conception to disposal through design,manufacture, use and service. The goal of product lifecycle management plm is to provide an infrastructure that companies can use to improve product quality. If ipth is above target and increased or decreased by less than 30%, increase dose by 2 to 4 mcg iv every 2 to 4 weeks. Paricalcitol is used to treat and prevent hyperparathyroidism in patients with chronic kidney disease who are on dialysis. Each ml contains paricalcitol, 2 mcg or 5 mcg and the following inactive ingredients. Zemplar is available as a sterile, clear, colorless, aqueous solution for intravenous injection.
Zemplar is a drug marketed by abbvie and is included in two ndas. At the time, engineering data management software edms and later pdm allowed users to organize their product data, and apply rules for item identification and revision control. Zemplar paricalcitol injection, solution abbott laboratories zemplar paricalcitol injection fliptop vial. Paricalcitol is not recommended for the routine treatment of secondary hyperparathyroidism in patients with ckd. Common features of product lifecycle management software the modules and features found within plm applications will vary vendor by vendor. Zemplar capsules, 2 micrograms, is an oval, orangebrown soft capsule imprinted with 3 and zf. Break down organizational silos with product lifecycle management software to increase efficiency, cut costs, improve quality, and drive innovation. No matter what role you play in the engineering department, whether product development, software development or systems engineering. Finally, in 1980, unigraphics was released, marking the groups first true 3d modeling hardware and software offering. Product lifecycle management plm is the process of managing the entire lifecycle of a product from its conception, through design and manufacture, to service and disposal. Us anda litigation and generic entry outlook for zemplar. Mar 10, 2010 study of zemplar iv in patients with end stage chronic kidney disease, undergoing haemodialysis the safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Paricalcitol injection zemplar side effects, medical uses. Product lifecycle management plm software manages products throughout conception, design, manufacturing, service and decommission.
Zemplar capsules are used to prevent and treat secondary hyperparathyroidism increased parathyroid hormone levels in adults and children 10 years of age and older with stage 3 or stage 4 chronic kidney disease and in stage 5 patients on dialysis. Zemplar paricalcitol dosing, indications, interactions, adverse. There are ten drug master file entries for this compound. Paricalcitol versus calcitriol in the treatment of. Zemplar fda prescribing information, side effects and uses.
A userfriendly, flexible and scalable software that helps you face all your. Iv bolus dose no more frequently then every other day at any time during dialysis. Read more about the prescription drug paricalcitol injection. Home summ systems ab siemens plm software solution partner.
It has full isobus compatibility and can be used to both control key vehicle functions and run precision applications, such as intellisteer auto guidance, as applied mapping and. Top 10 product lifecycle management software business. Zemplar 5 microgramml solution for injection summary. Top 10 plm and engineering software vendors, market size and. Zemplar is available as soft gelatin capsules for oral administration containing 1 microgram or 2 micrograms of paricalcitol. Oct 08, 2019 individualize and titrate zemplar dose based on ipth, serum calcium and phosphorus levels to maintain an ipth level within target range. Use plm software to create better designs, with improved processes and collaboration. Effectiveness and safety of iv zemplar in patients on hemodialysis and with secondary hyperparathyroidism using ipth100 as initial dose. New holland intelliview iv display new holland rochester. Oct 23, 2019 zemplar paricalcitol injection, for intravenous use initial u. Top 10 plm and engineering software vendors, market size. Summ systems ab is a siemens plm software solution partner siemens plm softwares product lifecycle management plm solutions include digital product.
Dose will be adjusted by 24 mcg every 4 weeks according to the parathyroid hormone level. This plm website has been created to serve you, providing online information and services for the new holland precision land management range of products. Zemplar definition of zemplar by medical dictionary. This website allows you to get the most from using new holland dgps products. Paricalcitol oral is for use in adults and children at least 10 years old. Paricalcitol injection fda prescribing information, side. Zemplar is administered as an intravenous bolus injection. Effectiveness and safety of iv zemplar in patients on hemodialysis. Information that is in the siemens plm licensing user guide supersedes any information in the flexera guide. Retail fashion and apparel plm software ngc software. The product repository manages finished products, recipes, raw materials and packaging with their technical and regulatory data. Preclinical and in vitro studies have demonstrated that paricalcitols biological actions are mediated through binding of the vitamin d receptor vdr, which results in the selective activation of vitamin d responsive pathways. Product lifecycle management plm software comparison report. Zemplar paricalcitol dosing, indications, interactions.
Healtheconomic comparison of paricalcitol, calcitriol and. Product lifecycle management plm is an integrated, informationdriven approach to all aspects of a products life from its design inception through its manufacture, deployment and maintenance, culminating in its remova. The most common adverse reaction associated with zemplar therapy was hypercalcaemia, occurring in 4. Paricalcitol injection zemplar side effects, medical. Find patient medical information for zemplar intravenous on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Zemplar injection fda prescribing information, side effects. Nov 28, 2019 the six youngest zemplar iv treated patients in the study were 5 12 years old.
Paricalcitol is the generic ingredient in two branded drugs marketed by amneal pharms, aurobindo pharma ltd, bionpharma inc, dr reddys labs ltd, lotus pharm co ltd, marksans pharma, rising, teva pharms usa, abbvie, accord hlthcare, akorn, amneal pharms co, dr reddys, hikma pharms, hospira inc, mylan labs ltd, and sandoz inc, and is included in. What are the possible side effects of paricalcitol zemplar. Listing a study does not mean it has been evaluated by the u. Siemens plm licensing user guide 3 siemens plm licensing user guide siemens plm licensing user guide disclaimer we are providing the flexera license administration guide as it was distributed by flexera software incorporated. Paricalcitol injection is for use in adults and children at least 5 years old. Hypercalcaemia is dependent on the level of pth oversuppression and. As the name indicates, product lifecycle management plm software helps companies to manage their products lifecycle from design and development to disposal at the end. Quickly find the best plm software for your business needs buy a product lifecycle management plm software comparison report from tec to get a jump on analyzing and comparing the features and functionsalong with software vendors support levelsfor all the currently available plm solutions. Requires an activation key that can be purchased from your local new holland dealer. Product lifecycle management applications enable key stakeholders including designers, engineers and oems to gain and optimize visibility into the entire product life cycle from idea generation to collaboration and from product data management to iterative development efforts. Siemens plm licensing user guide femto engineering.
Effectiveness and safety of iv zemplar in patients on. Zemplar 5 microgramml solution for injection summary of. C indications prevention and treatment of secondary hyperparathyroidism in patients with stage 3 or 4 po or stage 5 po and iv chronic kidney disease. The most common side effects with the use of zemplar capsules include diarrhea, inflammation of the nose and throat, dizziness, vomiting, high blood pressure, allergic reaction, nausea, and swelling. Every 4 weeks, each administered zemplar dose may be increased in 1 mcg increments, maintaining the three times per week regimen e. Todays top 164 siemens plm software jobs in united states.
In 2018, the top 10 product lifecycle management and engineering software vendors accounted for nearly 80. It helps your body maintain the right amount of calcium and phosphorus for healthy bones and teeth. What should i discuss with my healthcare provider before using paricalcitol zemplar. Limited data with paricalcitol injection in pregnant women are insufficient to inform a drugassociated risk for major birth defects and miscarriage. Zemplar paricalcitol injection, for intravenous use. Additional details are available on the paricalcitol profile page. It is available as a sterile, clear, colorless, aqueous solution for intravenous injection. Plm software product lifecycle management software. Plm mapping formula rx desktop software by new holland north america. About zemplar paricalcitol capsules 1 what is zemplar. Each carton contains either 1 or 4 foil blister packs.
Use this link if you already have the software on your computer. Refractory secondary hyperparathyroidism including. May 01, 2009 effectiveness and safety of iv zemplar in patients on hemodialysis and with secondary hyperparathyroidism using ipth100 as initial dose the safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Role of plm plm solutions like siemens plm software s teamcenter software play a crucial role in ensuring that hightech and electronics companies are able to define. Seair offers latest zemplar import data and directory of zemplar importers, exporters, buyers, suppliers, and manufacturers in india. Find patient medical information for zemplar oral on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Originally, engineering data was relatively simple. Plm software service pack update for existing users download your copy of plm software compatible with microsoft windows. This is the most important information to know about zemplar capsules. Cinacalcet at sites with iv paricalcitol participants in the iv stratum received 30 mg of oral cinacalcet daily with a lowdose vitamin d receptor activator vdra doxercalciferol iv 1 mcg 3 times weekly tiw at sites in the us and alfacalcidol capsules 0. J2501 hcpcs code paricalcitol hcpcs registry medical.
The intelliview iv display is an intuitive, color touchscreen display that can be factoryintegrated in numerous models of new holland equipment. The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Evaluation of the effectiveness of paricalcitol versus. Each 1 ml ampoule contains 5 micrograms of paricalcitol. Download the top 10 product lifecycle management software report for our comparison of the top plm software solutions. Paricalcitol, usp, the active ingredient in zemplar injection, is a synthetically manufactured analog of calcitriol, the metabolically active form of vitamin d indicated for the prevention and treatment of. Paricalcitol is a manmade active form of vitamin d, which is needed for building and keeping strong bones.
1369 71 262 241 1100 1333 807 570 1066 775 962 1056 300 262 590 1109 1392 308 1184 1108 1416 943 927 1127 688 285 1428 550 168 1129 1310 644 1397 223 688 769 141 68 1323 821